References & Attribution - IUPHAR Guide to PHARMACOLOGY (NC-IUPHAR)

https://www.guidetopharmacology.org/

The Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR) defines the official receptor nomenclature and classification system for G protein-coupled receptors (Class A, B1, B2, C, F). NC-IUPHAR's classifications are curated and disseminated through the IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb).

AlephConforma did not query the GtoPdb API directly. Class labels used in our per-class validation breakdown were retrieved from the GPCRdb REST API, which adopts the NC-IUPHAR nomenclature (see the GPCRdb entry).

GtoPdb data is licensed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) license; the database itself is licensed under the Open Data Commons Open Database License (ODbL) (about page, citing).

1. Harding SD, Armstrong JF, Faccenda E, Southan C, Alexander SPH, Davenport AP, Spedding M, Davies JA. (2025) The IUPHAR/BPS Guide to PHARMACOLOGY in 2026. Nucleic Acids Research 54(D1):D1446-D1456 (2026). doi:10.1093/nar/gkaf1067